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无家可归的精神病患者的自杀意念和自杀未遂:特定年龄的药物滥用风险。

Suicidal ideation and suicide attempts in homeless mentally ill persons: age-specific risks of substance abuse.

作者信息

Prigerson Holly G, Desai Rani A, Liu-Mares Wen, Rosenheck Robert A

机构信息

VISN 1 Mental Illness Research, Education and Clinical Center, Veterans Affairs Medical Center (182), West Haven, CT, USA.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2003 Apr;38(4):213-9. doi: 10.1007/s00127-003-0621-8.

Abstract

BACKGROUND

Despite reports of high rates of suicidal behavior among mentally ill homeless persons, it remains unknown whether the well-established suicide risks of increased age and comorbid psychiatric and substance abuse disorders ("dual diagnosis") documented in the general population are also markers for increased suicide risk among homeless persons.

METHODS

Data from a multi-site outreach program (ACCESS) (N = 7,224) were used to investigate whether rates of serious suicidal ideation and recent suicide attempts varied with the age and substance abuse diagnosis(es) (drug abuse and/or alcohol abuse disorders) among homeless mentally ill clients.

RESULTS

The prevalence of 30-day suicidal ideation and suicide attempts (37.5 % and 7.9 %, respectively) was extremely high. Although the risk of serious suicidal ideation and suicide attempts was greater among the younger compared with the older homeless mentally ill clients, risks were not significantly increased by co-morbid alcohol and/or drug abuse. However, a significant interaction between age and co-morbid substance abuse was observed showing that among older clients but not younger clients, those with drug and alcohol abuse were at significantly greater risk of suicidal ideation than those without substance use problems, controlling for confounding factors.

CONCLUSION

Efforts to prevent suicide should recognize that among homeless people with mental illness, young-middle-aged (30- to 39-year-old) clients are at greatest risk of suicidal behavior. Among older clients the presence of both drug and alcohol abuse significantly increases suicide risk. These patterns are of special importance because they are quite different from those that are well documented in non-homeless populations.

摘要

背景

尽管有报告称患有精神疾病的无家可归者自杀行为发生率很高,但在普通人群中已得到充分证实的年龄增长以及合并精神疾病和物质滥用障碍(“双重诊断”)导致自杀风险增加的情况,在无家可归者中是否也是自杀风险增加的标志仍不清楚。

方法

来自一个多地点外展项目(ACCESS)(N = 7224)的数据被用于调查患有精神疾病的无家可归者中,严重自杀意念和近期自杀未遂的发生率是否随年龄和物质滥用诊断(药物滥用和/或酒精滥用障碍)而变化。

结果

30天内自杀意念和自杀未遂的发生率(分别为37.5%和7.9%)极高。虽然与年龄较大的患有精神疾病的无家可归者相比,年龄较小者出现严重自杀意念和自杀未遂的风险更大,但合并酒精和/或药物滥用并不会显著增加风险。然而,观察到年龄与合并物质滥用之间存在显著交互作用,表明在年龄较大的患者中,而非年龄较小的患者中,在控制混杂因素后,同时存在药物和酒精滥用的患者自杀意念风险显著高于无物质使用问题的患者。

结论

预防自杀的努力应认识到,在患有精神疾病的无家可归者中,中青年(30至39岁)患者自杀行为风险最高。在年龄较大的患者中,药物和酒精滥用同时存在会显著增加自杀风险。这些模式尤为重要,因为它们与非无家可归人群中充分记录的模式有很大不同。

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