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[白内障手术后内皮细胞丢失的远期结果]

[Late results of endothelial cell loss after cataract surgery].

作者信息

Lesiewska-Junk Hanna, Malukiewicz-Wiśniewska Grazyna

机构信息

Kliniki Chorób Oczu Akademii Medycznej w Bydgoszczy.

出版信息

Klin Oczna. 2002;104(5-6):374-6.

Abstract

PURPOSE

To evaluate endothelial cell loss rate after cataract surgery in 5 years-long period.

MATERIAL AND METHOD

The studied group comprised 115 patients (66 females and 49 males) who had undergone senile and presenile cataract surgery. Mean age was 60 years (SD = 90). In 60 patients extracapsular cataract extraction and in 55 phacoemulsification have been performed. Mean central corneal thickness was measured before and 2 days after cataract surgery. Mean central endothelial cell density was assessed preoperatively, as well as 1, 3, 6 months and 2, 5 years after operation.

RESULTS

Mean endothelial cell loss was: 76% 1 month after surgery, and 97% 3 months, 110% 6 months, 124% 2 years, 140% 5 years postoperatively.

CONCLUSIONS

Enhanced endothelial cell loss could be observed even 2 years after surgery. 5 years postoperatively physiological loss rate is attained. Initial postoperative increase in central corneal thickness is an important marker of subsequent endothelial cell loss.

摘要

目的

评估白内障手术后5年内内皮细胞丢失率。

材料与方法

研究组包括115例接受老年性和早老性白内障手术的患者(66例女性,49例男性)。平均年龄为60岁(标准差=9.0)。60例患者行白内障囊外摘除术,55例患者行超声乳化术。在白内障手术前及术后2天测量平均中央角膜厚度。术前以及术后1、3、6个月和2、5年评估平均中央内皮细胞密度。

结果

术后1个月平均内皮细胞丢失率为76%,3个月为97%,6个月为110%,2年为124%,5年为140%。

结论

术后2年甚至可观察到内皮细胞丢失增加。术后5年达到生理性丢失率。术后初期中央角膜厚度增加是随后内皮细胞丢失的重要标志。

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