Wilczynski Michal, Supady Ewa, Loba Piotr, Synder Aleksandra, Palenga-Pydyn Dorota, Omulecki Wojciech
Department of Ophthalmology, Medical University of Lodz, Lodz, Poland.
J Cataract Refract Surg. 2009 Sep;35(9):1570-4. doi: 10.1016/j.jcrs.2009.05.014.
To compare corneal endothelial cell loss after coaxial 1.8 mm microincision cataract surgery (MICS) and bimanual 1.7 mm MICS.
Department of Ophthalmology, Medical University of Lodz, Lodz, Poland.
The study comprised a nonrandomized prospective consecutive series of 51 eyes of 51 patients who had coaxial MICS with implantation of an MI60 foldable intraocular lens (IOL) using a 1.8 mm temporal clear corneal microincision. Fifty eyes of 50 patients who had uneventful bimanual MICS through a 1.7 mm temporal clear corneal incision for a sleeveless phaco tip and a side port for an irrigating chopper with a foldable Acri.Smart 48S foldable IOL implantation served as a reference group. Corneal endothelial cell density, intraoperative phaco power, effective phaco time, and preoperative and postoperative visual acuities were evaluated. The measurements were performed in a semiautomated masked manner. Statistical analysis was done using nonparametric tests (Wilcoxon signed rank test and Mann-Whitney U test).
The patients were examined preoperatively and 2 weeks to 1 month postoperatively. The mean follow-up was 22.58 days +/- 5.08 (SD). Postoperatively, the mean corrected distance visual acuity (CDVA)was 0.95 +/- 13 in both groups. There was a significant decrease in endothelial cell density in both groups, 9.46% in Group 1 and 9.27% in Group 2. The between-group difference was not statistically significant (P>.05, Mann-Whitney U test).
The visual results were excellent in both groups. Both MICS techniques enabled preservation of corneal endothelial cells equally well and were similar in terms of minor surgical trauma and the influence of surgery on corneal endothelial cell density. Our results support the use of both MICS techniques for cataract surgery.
比较同轴1.8mm微小切口白内障手术(MICS)和双手操作1.7mm MICS术后角膜内皮细胞损失情况。
波兰罗兹医科大学眼科。
本研究为非随机前瞻性连续系列研究,纳入51例患者的51只眼,这些患者接受了同轴MICS,并通过1.8mm颞侧透明角膜微小切口植入MI60可折叠人工晶状体(IOL)。50例患者的50只眼作为参照组,这些患者通过1.7mm颞侧透明角膜切口进行了顺利的双手操作MICS,使用无袖套超声乳化针头和用于冲洗切碎器的侧切口,并植入了可折叠的Acri.Smart 48S可折叠IOL。评估角膜内皮细胞密度、术中超声乳化能量、有效超声乳化时间以及术前和术后视力。测量以半自动遮蔽方式进行。使用非参数检验(Wilcoxon符号秩检验和Mann-Whitney U检验)进行统计分析。
患者在术前以及术后2周至1个月接受检查。平均随访时间为22.58天±5.08(标准差)。术后,两组的平均矫正远视力(CDVA)均为0.95±13。两组的内皮细胞密度均显著下降,第1组下降9.46%,第2组下降9.27%。组间差异无统计学意义(P>0.05,Mann-Whitney U检验)。
两组的视觉效果均极佳。两种MICS技术均能同样良好地保护角膜内皮细胞,在轻微手术创伤以及手术对角膜内皮细胞密度的影响方面相似。我们的结果支持在白内障手术中使用这两种MICS技术。