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[利用被动血凝反应测定天花初种和复种疫苗中的抗天花抗体]

[Use of the passive hemaglutination reactions for the determination of anti-smallpox antibodies in primary vaccination and revaccination against smallpox].

作者信息

Marennikova S S, Shenkman L S, Shelukhina E M, Matsevich G R, Nikulina V G

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1976 Feb(2):38-42.

PMID:1266465
Abstract

The authors present the results of studying the PHAT sensitivity in comparison with the neutralization test and the hemagglutination inhibition test in examination of 254 sera of revaccinated and 95 sera of primarily vaccinated children. It appeared that PHAT was characterized by a sufficiently high sensitivity, and reproducibility, in case the same batch of erythrocytic diagnostic agent was used; at the same time the test was simple, accessible, economic, and gave rapid results. This test can be used for assessment of the immunological efficacy of smallpox revaccination.

摘要

作者介绍了在检测254份再次接种疫苗儿童的血清和95份初次接种疫苗儿童的血清时,将PHA试验与中和试验及血凝抑制试验相比较研究PHA试验敏感性的结果。结果表明,在使用同一批次红细胞诊断试剂的情况下,PHA试验具有足够高的敏感性和可重复性;同时,该试验操作简单、易于实施、经济且结果快速。该试验可用于评估天花再次接种疫苗的免疫效果。

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