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[阿扎芬影响下老年期精神病临床病理生理特征的动态变化]

[Dynamics of the clinico-pathophysiologic characteristics of psychoses in old age under the influence of azafen].

作者信息

Taranskaia A D

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(3):440-3.

PMID:1266520
Abstract

A study of singular doses and subsequent maintenance therapy by azafen on the higher nervous activity of mental patients in presenile age (67 cases) revealed that its action depends upon the dosage of the preparation and the nosological syndrome. A depressive involutional psychoses can be controlled by azafen in doses up to 75 mg daily. By dosages of 25 mg azafen reduces or cessates completely the syndrome of changed consciousness due to disorders of brain circulation. An arrest of a depressive syndrome in manic-depressive psychosis in old age can be attained by an introduction of 150-200 mg of azafen daily.

摘要

一项关于阿扎芬对老年前期精神病人(67例)高级神经活动的单次剂量及后续维持治疗的研究表明,其作用取决于制剂的剂量和疾病分类综合征。阿扎芬每日剂量达75毫克时可控制抑郁性更年期精神病。阿扎芬剂量为25毫克时可减轻或完全消除因脑循环障碍导致的意识改变综合征。通过每日服用150 - 200毫克阿扎芬可使老年躁狂抑郁症中的抑郁综合征得到缓解。

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