普萘洛尔所致阵挛性抽搐抑制
Clonus depression by propranolol.
作者信息
Mai J, Pedersen E
出版信息
Acta Neurol Scand. 1976 May;53(5):395-8. doi: 10.1111/j.1600-0404.1976.tb04358.x.
Abstract
Propranolol administered i.v. to spastic patients was found to be capable of depressing clonus. The drug exerts its action on the spinal cord but does not influence dynamic spindle activity or alpha-motoneurone activity as tested by the T (Achilles tendon) and H reflexes. It may disinhibit the tonic stretch reflex. Thus, clonus is dependent not only on dynamic spindle activity but also on another, probably inhibitory, mechanism.
摘要
静脉注射普萘洛尔给痉挛患者后，发现该药能够抑制阵挛。该药物对脊髓起作用，但不影响通过T（跟腱）反射和H反射测试的动态肌梭活动或α运动神经元活动。它可能解除对紧张性牵张反射的抑制。因此，阵挛不仅依赖于动态肌梭活动，还依赖于另一种可能是抑制性的机制。
Zotero 插件