Murray T J
Can Med Assoc J. 1981 Jun 15;124(12):1559-65, 1570.
Essential tremor, including the juvenile and senile variations, may be a result of a disorder of the servomechanism that controls physiologic tremor. Hands and arms are affected most commonly, and the tremor can vary in amplitude as well as frequency. Long-term treatment with propranolol has been helpful for some patients, although older patients are less likely to benefit. Other drugs and behaviour modification therapy have been less successful. Surgical treatment is effective but should probably be reserved for severe cases. An effective instrument for measuring the subjective and objective aspects of the tremor is still needed, as is an effective long-term method of treatment.
特发性震颤,包括青少年型和老年型,可能是控制生理性震颤的伺服机制紊乱所致。手部和手臂最常受累,震颤的幅度和频率可能会有所不同。普萘洛尔长期治疗对一些患者有帮助,尽管老年患者受益的可能性较小。其他药物和行为矫正疗法效果较差。手术治疗有效,但可能应仅用于严重病例。仍然需要一种有效的仪器来测量震颤的主观和客观方面,以及一种有效的长期治疗方法。