Tene Carlos Enrique, Espinoza-Mejía Martha Yaneth, Silva-Rosales Norma Angélica, Girón-Carrillo Jorge Luis
Unidad de Investigación Médica en Epidemiología Clínica del Hospital General de Zona y Medicina Familiar # 1 del IMSS Colima, Calle Luis G Urbina 624, Colonia Lomas de Vista Hermosa, Código Postal 28040, Colima Colima.
Gac Med Mex. 2003 Jan-Feb;139(1):15-20.
To investigate the association between high birth weight (HBW) and childhood obesity (CO).
A case-control study in 322 children of 1st and 2nd grade elementary school was carried out. Somatometric determinations were effected to document childhood obesity (cases) as established by The Norma Oficial Mexicana, and normal or low weight. The risk factor of HBW (high birth weight more than 3900 g) was assessed. Odds ratio (OR) was determined and variables between cases and controls were assessed by chi 2 and t tests.
There were not clinically significative differences between cases (n = 59) and controls (n = 263) concerning sex, age, height, and weight at birth. There were differences as to present weight (35.5 +/- 8 vs 25.2 +/- 5 kg. p < 0.001), Quetelet index (22.1 +/- 4 vs 16.2 +/- 2 kg/m2, p < 0.001) and measurements of cutaneous folding between cases and controls, respectively. History of HBW was present in 20 cases (33%) and 44 controls (17%). History of HBW was associated to CO [OR: 2.55; (Confidence interval [CI] 95% 1.4-4.8); p = 0.003]. No history of HBW was protective against CO [OR: 0.79; (CI 95% 0.7-0.9); p = 0.003].
HBW is risk factor to CO.
探讨高出生体重（HBW）与儿童肥胖（CO）之间的关联。
对322名小学一、二年级儿童进行了病例对照研究。进行了人体测量以记录按照墨西哥官方标准确定的儿童肥胖（病例组）以及正常体重或低体重情况。评估了高出生体重（出生体重超过3900克）这一风险因素。确定了优势比（OR），并通过卡方检验和t检验评估病例组与对照组之间的变量。
病例组（n = 59）和对照组（n = 263）在性别、年龄、出生时身高和体重方面无临床显著差异。病例组与对照组在当前体重（35.5±8 vs 25.2±5千克，p < 0.001）、克托莱指数（22.1±4 vs 16.2±2千克/平方米，p < 0.001）以及皮肤褶皱测量方面存在差异。20例病例（33%）和44例对照组（17%）有高出生体重史。高出生体重史与儿童肥胖相关[OR：2.55；（95%置信区间[CI] 1.4 - 4.8）；p = 0.003]。无高出生体重史对儿童肥胖有保护作用[OR：0.79；（CI 95% 0.7 - 0.9）；p = 0.003]。
高出生体重是儿童肥胖的危险因素。
