Hund E
Neurologische Klinik, Ruprecht-Karls-Universität Heidelberg.
Anaesthesiol Reanim. 2003;28(1):4-7.
Chronic alcohol abuse causes several distinct diseases of the central and peripheral nervous system. Widely known are the alcohol withdrawal syndrome, alcohol-induced epileptic seizures, alcoholic polyneuropathy and myopathy, and Wernicke's encephalopathy. Beside these complications, less common syndromes have been identified, including Marchiafava-Bignami syndrome, subacute encephalopathy with seizure activity (SESA syndrome), and tobacco alcohol amblyopia. These syndromes can be diagnosed by their characteristic features in cranial MRI or in EEG. Moreover, certain disorders in which alcohol abuse is only indirectly involved in the pathogenesis are more frequent in alcoholics than in nonalcoholics. In daily practice, it is important to differentiate these disorders when encountering patients with chronic alcohol abuse.
长期酗酒会引发中枢神经系统和周围神经系统的多种不同疾病。广为人知的有酒精戒断综合征、酒精性癫痫发作、酒精性多发性神经病和肌病以及韦尼克脑病。除了这些并发症外,还发现了一些不太常见的综合征,包括马基亚法瓦-比尼亚米综合征、伴有癫痫活动的亚急性脑病(SESA综合征)和烟酒性弱视。这些综合征可通过头颅磁共振成像(MRI)或脑电图(EEG)的特征性表现来诊断。此外,某些酒精滥用仅间接参与发病机制的疾病在酗酒者中比在非酗酒者中更为常见。在日常实践中,遇到慢性酗酒患者时,区分这些疾病很重要。