Grygorczuk Sambor, Mierzyńska Dorota, Zdrodowska Agnieszka, Zajkowska Joanna, Pancewicz Sławomir, Kondrusik Maciej, Swierzbińska Renata, Pryszmont Justyna, Hermanowska-Szpakowicz Teresa
Klinika Chorób Zakaźnych i Neuroinfekcji Akademii Medycznej w Białymstoku.
Przegl Epidemiol. 2002;56(4):595-604.
To characterize epidemiological and clinical features of TBE in the Northeastern Poland.
Analysis of clinical and epidemiological data of patients hospitalized with the diagnosis of TBE in the Department of the Infectious Diseases and Neuroinfections of the Medical University in Białystok in 2001.
TBE was diagnosed in 48 patients. From that number 18 (37.5%) presented symptoms of meningitis, 24 (50.0%) meningoencephalitis, 5 (10.4%) meningoencephalomyelitis and 1 (2.1%) meningoencephaloradiculitis.
Headache (100%) and fever (87.5%) were the most common complaints. Signs of meningitis were observed in 35 patients (72.9%). Common neurological abnormalities were Oppenheim and Babinski signs (18 patients, 37.5%), pareses (8; 16.7%), ataxia (7; 14.58%) and impaired consciousness (6; 12.5%). Cytosis in cerebrospinal fluid (csf) was observed in all patients, frequently accompanied by high csf protein concentration, raised erythrocyte sedimentation rate (61.5%), leucocytosis (31.25%) and aminotrasferase activity (12.5%). There were no professional forest workers among the patients.
描述波兰东北部蜱传脑炎(TBE)的流行病学和临床特征。
分析2001年在比亚韦斯托克医科大学传染病与神经感染科住院治疗且诊断为TBE的患者的临床和流行病学数据。
48例患者被诊断为TBE。其中18例(37.5%)出现脑膜炎症状,24例(50.0%)出现脑膜脑炎症状,5例(10.4%)出现脑膜脑脊髓炎症状,1例(2.1%)出现脑膜脑神经根炎症状。
头痛(100%)和发热(87.5%)是最常见的主诉。35例患者(72.9%)出现脑膜炎体征。常见的神经异常体征有奥本海姆征和巴宾斯基征(18例患者,37.5%)、轻瘫(8例;16.7%)、共济失调(7例;14.58%)和意识障碍(6例;12.5%)。所有患者脑脊液均出现细胞增多,常伴有脑脊液蛋白浓度升高、红细胞沉降率升高(61.5%)、白细胞增多(31.25%)和转氨酶活性升高(12.5%)。患者中没有职业森林工人。