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用萨罗治疗的比格犬尿中苯酚水平升高。

Elevated urinary phenol levels in beagle dogs treated with salol.

作者信息

Kociba R J, Kalnins R V, Wade C E, Garfield E L, Fishbeck W A

出版信息

Am Ind Hyg Assoc J. 1976 Mar;37(3):183-90. doi: 10.1080/0002889768507441.

DOI:10.1080/0002889768507441
PMID:1266737
Abstract

Dogs administered 500 or 250 mg of salol/kg/day showed transient toxicity of a reversible nature. Doses of 125 mg salol/kg/day caused no discernible ill effects in spite of urinary phenol levels elevated as high as 6144 ppm. It appears as if exposure to a compound other than benzene can cause an elevation of urinary phenol.

摘要

每日每千克体重给予500毫克或250毫克萨罗的犬只表现出可逆性的短暂毒性。尽管尿酚水平高达6144 ppm,但每日每千克体重给予125毫克萨罗未产生明显不良影响。似乎接触苯以外的化合物也可导致尿酚升高。

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引用本文的文献

1
[Problems in the biological monitoring of benzene exposure].
Soz Praventivmed. 1984;29(1):44-5. doi: 10.1007/BF02301724.
2
Quantitative relation of urinary phenol levels to breathzone benzene concentrations: a factory survey.尿中苯酚水平与呼吸带苯浓度的定量关系:一项工厂调查。
Br J Ind Med. 1986 Oct;43(10):692-7. doi: 10.1136/oem.43.10.692.