Catcheside D G
Aust J Biol Sci. 1975 Apr;28(2):213-25. doi: 10.1071/bi9750213.
Each of the main laboratory wild stocks of N. crassa carries one of two alleles at the rec-1 and rec-2 loci and one of three at the rec-3 locus. The constitutions of the stocks are given in Fig. 1. Some of those conserved are evidently not the originals. The third rec-3 gene (rec-3L), found in Lindegren A, controls recombination at the am-1 locus to a level between that of rec-3+ and rec-3, the relative levels being 1 : 8 : 25. At the his-2 locus rec-3L is indistinguishable from rec-3+ in its level of control. This proves that there are minor differences between the control (con) genes, near to am-1 and his-2, which recognize products of rec-3 genes. Further, this is the first clear evidence, though indirect, that the binding sites for products of rec genes are situated in the chromosome regions where recombination is modulated.
粗糙脉孢菌的每个主要实验室野生菌株在rec - 1和rec - 2位点携带两个等位基因中的一个，在rec - 3位点携带三个等位基因中的一个。菌株的组成见图1。其中一些保存下来的显然不是原始的。在林德格伦A中发现的第三个rec - 3基因（rec - 3L），控制am - 1位点的重组，使其水平介于rec - 3 +和rec - 3之间，相对水平为1 : 8 : 25。在his - 2位点，rec - 3L在控制水平上与rec - 3 +无法区分。这证明在靠近am - 1和his - 2的控制（con）基因之间存在微小差异，这些基因识别rec - 3基因的产物。此外，这是第一个明确的证据，虽然是间接的，但表明rec基因产物的结合位点位于重组受到调控的染色体区域。
