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本文引用的文献

1
Gene Conversion in the Pasadena Strain of ASCOBOLUS IMMERSUS.浸没嗜热放线菌帕萨迪纳菌株中的基因转换
Genetics. 1967 Jan;55(1):39-47. doi: 10.1093/genetics/55.1.39.
2
Allelic pairing and gene regulation: A model for the zeste-white interaction in Drosophila melanogaster.等位基因配对与基因调控：黑腹果蝇中zeste-white相互作用的模型。
Proc Natl Acad Sci U S A. 1979 Mar;76(3):1368-72. doi: 10.1073/pnas.76.3.1368.
3
Controlling elements and the gene.控制元件与基因
Cold Spring Harb Symp Quant Biol. 1956;21:197-216. doi: 10.1101/sqb.1956.021.01.017.
4
Regulation of recombination at the his-3 locus in Neurospora crassa.粗糙脉孢菌中his-3基因座处重组的调控。
Aust J Biol Sci. 1970 Dec;23(6):1229-40. doi: 10.1071/bi9701229.
5
Genetic control of flanking marker behaviour in an allelic cross of Neurospora crassa.
Can J Genet Cytol. 1969 Sep;11(3):558-66. doi: 10.1139/g69-064.
6
Studies with purple adenine mutants in Neurospora crassa. VI. The effects of differences in genetic background on ad-3A x ad-3B crosses.粗糙脉孢菌紫色腺嘌呤突变体的研究。VI. 遗传背景差异对ad-3A×ad-3B杂交的影响。
Genetics. 1971 Jul;68(3):383-400. doi: 10.1093/genetics/68.3.383.
7
The suppression of gene conversion and intragenic crossing over in Ascobolus immersus: evidence for modifiers acting in the heterozygous state.浸没状粪壳菌中基因转换和基因内交换的抑制：杂合状态下起作用的修饰基因的证据。
Genetics. 1974 Feb;76(2):221-43. doi: 10.1093/genetics/76.2.221.
8
A histidine-3 mutant, in Neurospora crassa, due to an interchange.粗糙脉孢菌中由于一次互换产生的组氨酸-3突变体。
Aust J Biol Sci. 1974 Apr;27(2):219-29. doi: 10.1071/bi9740219.
9
Control of non-allelic recombination in Neurospora crassa.粗糙脉孢菌中非等位基因重组的调控
Aust J Biol Sci. 1973 Dec;26(6):1337-53. doi: 10.1071/bi9731337.
10
A general model for genetic recombination.遗传重组的通用模型。
Proc Natl Acad Sci U S A. 1975 Jan;72(1):358-61. doi: 10.1073/pnas.72.1.358.

脉孢菌中杂合时抑制重组的基因。

Genes in Neurospora that suppress recombination when they are heterozygous.

作者信息

Catcheside D E

出版信息

Genetics. 1981 May;98(1):55-76. doi: 10.1093/genetics/98.1.55.

DOI:10.1093/genetics/98.1.55
PMID:6461572
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1214434/
Abstract

Genes that suppress recombination when heterozygous have been found distributed as a polymorphism in wild and laboratory populations of Neurospora crassa. Three alleles, ssE, ssS and ssC, are associated, respectively, with th the three wild types Emerson, St. Lawrence 74A and Costa Rica A. It is proposed that ss (synaptic sequence) genes modulate recombination by determining the pairing closeness of DNA duplexes in the vicinity of the nit-2 locus. When heterozygous, ss suppresses recombination 2- to 20-fold within the nit-2 locus, which it adjoins, but crossing over in intervals flanking nit-2 is not affected. The magnitude of suppression depends upon the ss alleles involved, and ss acts multiplicatively with rec-1; together, these genes modulate recombination within the nit-2 locus over a range exceeding 100-fold. The ss effect is not attributable to gross chromosomal rearrangement, but could be due to small inversions or insertions, such as transposable elements.

摘要

已发现杂合时抑制重组的基因作为一种多态性分布于粗糙脉孢菌的野生和实验室群体中。三个等位基因，即ssE、ssS和ssC，分别与三种野生型埃默森、圣劳伦斯74A和哥斯达黎加A相关联。有人提出，ss（突触序列）基因通过确定nit-2基因座附近DNA双链体的配对紧密程度来调节重组。杂合时，ss在与其相邻的nit-2基因座内抑制重组2至20倍，但nit-2两侧区间的交叉不受影响。抑制程度取决于所涉及的ss等位基因，并且ss与rec-1起相乘作用；这些基因共同调节nit-2基因座内超过100倍范围的重组。ss效应并非归因于染色体的大规模重排，而可能是由于小的倒位或插入，如转座元件。