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[健康受试者在适应高原低氧环境过程中造血功能的变化]

[Functional changes in hematopoiesis in healthy subjects during adaptation to a high altitude hypoxia].

作者信息

Muratalieva E A, Mamatov S M, Nartaeva A K, Kononets I E

机构信息

Kirgyz Cientific Centre of Haematology, Kirgyzstan.

出版信息

Ross Fiziol Zh Im I M Sechenova. 2003 Jan;89(1):37-42.

PMID:12669591
Abstract

In the article, findings of the studies of white blood in healthy subjects during a short-term adaptation to high altitude (per. Tuya-Ashu, 3200 m), are discussed. A 40-day adaptation of healthy people has led to positive shifts: an increase of the number of leukocytes with prevalence of the absolute count of neutrophiles and lymphocytes, as well as an activation of the latter during the first days of stay at high altitude. An effect of the high-altitude hypoxia resulted in intensification of erythropoiesis that manifests itself in an improvement of red cell hemoglobinization and a decrease of the degree of non-effective erythropoiesis. The data obtained support the data of the myelograms demonstrating an improvement of differentiation of white hematopoiesis.

摘要

本文讨论了健康受试者在短期适应高海拔(图亚-阿舒,海拔3200米)过程中白细胞研究的结果。健康人40天的适应过程导致了积极的变化:白细胞数量增加,中性粒细胞和淋巴细胞绝对计数占优势,并且在高海拔停留的最初几天淋巴细胞被激活。高海拔缺氧的影响导致红细胞生成增强,表现为红细胞血红蛋白化改善和无效红细胞生成程度降低。所获得的数据支持骨髓象数据,表明白细胞生成的分化得到改善。

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