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[产前应激大鼠垂体-肾上腺系统的行为特征及应激反应]

[Behavioral characteristics and stress reaction of the pituitary-adrenal system in prenatally stressed rats].

作者信息

Ordian N E, Pivina S G

机构信息

I. P. Pavlov Institute of Physiology, Russian Acad. Sci., 199034, St. Petersburg, Nab. Makarova, 6, Russia.

出版信息

Ross Fiziol Zh Im I M Sechenova. 2003 Jan;89(1):52-9.

Abstract

Mothers' stress was shown to considerably diminish the orienting-studying activity of male rats in the dioestrus stage, as well as enhancement of anxiety. In prenatally stressed male rats, on the contraty, the anxiety diminished while their behaviour in the open field tests remained practically unaltered. The prenatal stress affected the stressor response of the hypophysis-adrenal systems in both sexes. The data obtained suggest that the mothers' stress affects both behaviour and stressor response in male as well as female rats.

摘要

研究表明,母亲的压力会显著降低处于动情间期的雄性大鼠的定向学习活动,并加剧焦虑。相反,在产前受到压力的雄性大鼠中,焦虑减轻,而它们在旷场试验中的行为基本未变。产前压力影响了两性垂体 - 肾上腺系统对应激源的反应。所得数据表明,母亲的压力会影响雄性和雌性大鼠的行为及对应激源的反应。

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