Williams David L
Department of Pharmacological Sciences, University Medical Center, State University of New York, Stony Brook, NY 11794, USA.
Chem Biol. 2003 Mar;10(3):202-4. doi: 10.1016/s1074-5521(03)00054-1.
Scavenger receptor BI (SR-BI) is a high-density lipoprotein (HDL) receptor that mediates the selective uptake of HDL cholesteryl ester (CE) and the bidirectional flux of free cholesterol (FC). The identification of selective uptake inhibitors holds promise for mechanistic studies of SR-BI and for discovery of pharmaceuticals useful in therapy of atherosclerosis.
清道夫受体BI（SR-BI）是一种高密度脂蛋白（HDL）受体，可介导HDL胆固醇酯（CE）的选择性摄取以及游离胆固醇（FC）的双向流动。选择性摄取抑制剂的鉴定为SR-BI的机制研究以及发现可用于治疗动脉粥样硬化的药物带来了希望。
