Tsirikos Athanasios I, Riddle Eric C, Kruse Richard
Alfred I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19899, USA.
Clin Orthop Relat Res. 2003 Apr(409):195-8. doi: 10.1097/01.blo.0000057993.41099.d5.
Köhler's disease is an uncommon idiopathic osteochondrosis of the tarsal navicular bone. The diagnosis is clinical and the natural history is benign. The treatment is symptomatic, including shoe supports when the symptoms are mild and initial cast immobilization for at least 8 weeks when the symptoms are more intense. The final clinical outcome is always favorable. This article reviews the development of bilateral Köhler's disease in identical twin brothers with simultaneous onset and parallel clinical course. Bilateral involvement in identical twins, to the authors' knowledge, has not been reported in the literature. Although this is a preliminary finding, it can imply that an unknown genetic predilection may exist and relate to the appearance of this rare disease.
科勒氏病是一种罕见的舟状骨特发性骨软骨病。诊断依靠临床症状，其自然病程呈良性。治疗以对症治疗为主，症状较轻时使用鞋垫，症状较重时开始至少8周的石膏固定。最终临床结果总是良好的。本文回顾了一对同卵双胞胎兄弟同时发病且临床病程平行的双侧科勒氏病的发展情况。据作者所知，同卵双胞胎双侧受累的情况在文献中尚未有报道。尽管这是一个初步发现，但它可能意味着存在一种未知的遗传易感性，并且与这种罕见疾病的出现有关。
