Kawarada Y, Goldberg L, Brady L, Pavlides C, Matsumoto T
Am Surg. 1976 May;42(5):332-45.
We reviewed 39 patients with untreated Hodgkin's disease who underwent staging laparotomy and such cases in the English literature over the past two-and-a-half years. In the group of institutions in our compilation, the accuracies of clinically positive and negative judgments of liver involvement were 28 per cent and 95.4 per cent respectively, while in our institution the accuracies were 100 per cent and 95 percent respectively. The accuracies of the clinically positive and negative determinations of splenic involvement were 61.2 per cent and 67.3 per cent respectively after histological examination, whereas we had accuracies of 100 per cent and 74 per cent respectively. The accuracies of the clinically positive and negative determination of lymph nodes were 72.1 per cent and 86.7 per cent respectively, whereas the results were 70.6 per cent and 100 per cent respectively in our 39 cases. The percentage of complications was 10 per cent and the mortality rate was 0.9 per cent among 719 staging laparotomies. The common complications were atelectasis, pneumonia, wound infection and dehiscence, abscess, intestinal obstruction and thrombocytosis. We think more aggressive staging laparotomy should be performed for Hodgkin's disease under one surgeon or one surgical team.
我们回顾了39例未经治疗的霍奇金病患者,他们接受了分期剖腹探查术,并研究了过去两年半英文文献中报道的此类病例。在我们汇总的机构组中,对肝脏受累临床阳性和阴性判断的准确率分别为28%和95.4%,而在我们机构中,准确率分别为100%和95%。组织学检查后,对脾脏受累临床阳性和阴性判断的准确率分别为61.2%和67.3%,而我们的准确率分别为100%和74%。对淋巴结临床阳性和阴性判断的准确率分别为72.1%和86.7%,而在我们的39例病例中,结果分别为70.6%和100%。在719例分期剖腹探查术中,并发症发生率为10%,死亡率为0.9%。常见并发症有肺不张、肺炎、伤口感染和裂开、脓肿、肠梗阻和血小板增多症。我们认为,应由一名外科医生或一个手术团队对霍奇金病进行更积极的分期剖腹探查术。