Urlaub B J, Mack E
Ann Surg. 1979 Jul;190(1):45-7. doi: 10.1097/00000658-197907000-00010.
From 1971--1975, 107 staging laparotomies for Hodgkin's disease were performed at the University of Wisconsin Hospitals. Forty-one per cent of patients with abnormal abdominal lymphangiograms preoperatively had abdominal nodes which were negative for Hodgkin's. Thirteen per cent of patients with negative preoperative lymphangiograms had positive nodes at staging laparotomy. Twenty-nine per cent were upstaged by laparotomy, i.e. assigned to a less favorable stage (II A to III A), and 11.2% were downstaged. There were no surgical mortalities. Minor surgical complications occurred in 14.9%, and major ones in 3.7%. We conclude that surgical staging for Hodgkin's disease is valuable in making an accurate diagnosis and, hence, in determining the most effective treatment.
1971年至1975年期间,威斯康星大学医院对107例霍奇金病患者进行了分期剖腹探查术。术前腹部淋巴管造影异常的患者中,41%的患者腹部淋巴结霍奇金病检查呈阴性。术前淋巴管造影呈阴性的患者中,13%在分期剖腹探查时发现淋巴结阳性。29%的患者因剖腹探查而被上调分期,即被分配到预后较差的分期(从II A期到III A期),11.2%的患者被下调分期。无手术死亡病例。轻微手术并发症发生率为14.9%,严重手术并发症发生率为3.7%。我们得出结论,霍奇金病的手术分期对于准确诊断以及确定最有效的治疗方法具有重要价值。