Hughes G B, Chidi C C, Macon W L
Ann Surg. 1976 Apr;183(4):355-7. doi: 10.1097/00000658-197604000-00004.
One hundred patients with community-acquired staphylococcal infections of the skin and soft tissues were treated in the Emergency Ward of Cleveland Metropolitan General Hospital from June to October of 1974. Each staphylococcal infection was considered community-acquired if, within two weeks prior to being treated for the first time, the patient had not received antibiotics, had not been hospitalized, and had not been in contact with other recently hospitalized persons. Of 100 community-acquired staphylococcal infections, 85 were resistant to penicillin. Almost no resistance to other tested antibiotics was observed. Unless indicated otherwise by bacteriologic testing, penicillin is a poor drug of choice in those skin and soft tissue infections suspected of harboring staphylococci.
1974年6月至10月期间，100例社区获得性皮肤和软组织葡萄球菌感染患者在克利夫兰市立综合医院急诊科接受治疗。如果患者在首次接受治疗前两周内未接受过抗生素治疗、未住院且未与其他近期住院的人员接触，则每例葡萄球菌感染都被视为社区获得性感染。在100例社区获得性葡萄球菌感染中，85例对青霉素耐药。几乎未观察到对其他测试抗生素的耐药情况。除非细菌学检测另有指示，否则对于怀疑携带葡萄球菌的皮肤和软组织感染，青霉素不是一个好的选择药物。
