Rainero Innocenzo, Valfrè Walter, Gentile Salvatore, Lo Giudice Rossana, Ferrero Margherita, Savi Lidia, Pinessi Lorenzo
Neurology III, Headache Center, Department of Neuroscience, University of Turin, Italy.
Funct Neurol. 2002 Oct-Dec;17(4):193-7.
We compared the clinical, psychological and pharmacological characteristics of patients with familial migraine and patients with sporadic migraine. Five hundred and thirty consecutive new patients attending our Headache Center over a two-year period were involved in the study. The patients were divided into two groups: A. Familial migraine (famM)--at least one first-degree relative affected; B. Sporadic migraine (spoM)--no first-degree relative affected. Four hundred and twenty-four patients (80%) fulfilled the criteria for famM and 106 (20%) for spoM. The patients with famM showed a significantly (p<0.01) earlier age at onset of the disease. No significant difference in all the remaining features examined was found. Our data suggest that famM and spoM represent a single disease entity.
我们比较了家族性偏头痛患者和散发性偏头痛患者的临床、心理及药理学特征。在两年时间里，连续有530名新患者到我们的头痛中心就诊并参与了这项研究。患者被分为两组：A. 家族性偏头痛（famM）——至少有一位一级亲属患病；B. 散发性偏头痛（spoM）——无一级亲属患病。424名患者（80%）符合famM标准，106名患者（20%）符合spoM标准。famM患者发病年龄显著更早（p<0.01）。在其他所有检查特征方面未发现显著差异。我们的数据表明，famM和spoM代表单一疾病实体。
