Brown Heather M, McCutcheon Ian E, Leeds Norman E, Schomer Donald S, Luna Mario A, Fuller Gregory N
Department of Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, TX 77030, USA.
J Neurooncol. 2003 Feb;61(3):209-14. doi: 10.1023/a:1022599622949.
We report a case of a 43-year-old man with known metastatic melanoma and two intracranial tumors, one of which was resected and confirmed to be melanoma. At autopsy, the second lesion was found to be a central neurocytoma harboring metastatic melanoma. To our knowledge, this represents the first reported case of tumor-to-tumor metastasis to a central neurocytoma. The most common pattern of tumor-to-tumor metastasis for intracranial neoplasms, in which an aggressive high-grade malignancy serves as the source tumor and a more indolent neoplasm serves as the recipient tumor, is affirmed by the present novel example.
