Tally P W, Laws E R, Scheithauer B W
Department of Neurosurgery, Mayo Clinic Graduate School of Medicine, Rochester, Minnesota.
J Neurosurg. 1988 May;68(5):811-6. doi: 10.3171/jns.1988.68.5.0811.
Tumor-to-tumor metastasis is a rare occurrence. Fewer than 100 cases have been reported, many being metastases from carcinomas to benign intracranial neoplasms, most often meningiomas. A case is presented of carcinoma metastatic to a glioma. The patient, who presented for evaluation of bifrontal headache, was found on computerized tomography to have a partially calcified right frontal mass. Craniotomy revealed an oligodendroglioma containing foci of adenocarcinoma. Further work-up disclosed an infiltrative ductal adenocarcinoma of the breast. It has been suggested that tumors of the central nervous system may provide a fertile substrate or an immunological "haven" for metastases.
肿瘤至肿瘤转移是一种罕见情况。报告的病例少于100例，其中许多是癌转移至颅内良性肿瘤，最常见的是脑膜瘤。本文介绍了一例癌转移至胶质瘤的病例。该患者因双额部头痛前来评估，计算机断层扫描发现右侧额叶有一局部钙化肿块。开颅手术显示为少突胶质细胞瘤，其中含有腺癌灶。进一步检查发现为乳腺浸润性导管腺癌。有人提出，中枢神经系统肿瘤可能为转移提供肥沃的基质或免疫“庇护所”。
