Chand N, Eyre P
Arch Int Pharmacodyn Ther. 1976 Jan;219(1):13-28.
The effects of "M"-receptor blockers (atropine and morphine), "D"-receptor blockers (dibenamine, dibenzyline, methysergide) and a ganglion blocking agent (mecamylamine) were studied to characterize cardiovascular tryptaminergic receptors in domestic fowl. This study showed the presence of both "M" and "D" tryptaminergic receptors (both mediating systemic hypotension) and also other "D"-receptors, which mediate arterial and venous hypertensive responses to 5-HT. There appear to be interactions of tryptaminergic, cholinergic and adrenergic mechanisms in the mediation of cardiovascular responses to 5-HT in chicken.
研究了“M”受体阻滞剂（阿托品和吗啡）、“D”受体阻滞剂（双苄胺、苄基丙咪嗪、甲基麦角新碱）和一种神经节阻滞剂（美加明）的作用，以确定家禽心血管系统中色胺能受体的特征。该研究表明存在“M”和“D”色胺能受体（均介导全身性低血压）以及其他“D”受体，后者介导对5-羟色胺的动脉和静脉高血压反应。在鸡对5-羟色胺的心血管反应介导过程中，色胺能、胆碱能和肾上腺素能机制之间似乎存在相互作用。
