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西澳大利亚的马蹄内翻足

Talipes equinovarus in Western Australia.

作者信息

Carey Mary, Bower Caroline, Mylvaganam Arul, Rouse Ian

机构信息

School of Public Health, Curtin University, Perth, Western Australia.

出版信息

Paediatr Perinat Epidemiol. 2003 Apr;17(2):187-94. doi: 10.1046/j.1365-3016.2003.00477.x.

Abstract

In Western Australia (WA), talipes equinovarus is a notifiable birth defect and, since 1980, has been ascertained by the population-based Birth Defects Registry (BDR). Talipes equinovarus deformities were classified as two distinct and distinguishable types, viz. isolated talipes equinovarus (no other birth defects present) and associated talipes equinovarus (other birth defects present). The birth prevalence of associated talipes in WA between 1980 and 1994 was 0.90 per 1000 births, and of isolated talipes was 1.25 per 1000 births. The rate of the isolated deformity was higher in Aboriginal infants (3.49 per 1000 births) than in Caucasian infants (1.11 per 1000 births) and non-Aboriginal non-Caucasian infants (0.73 per 1000 births). The sex differential in the rate of the isolated deformity was greatest among Aboriginal infants, with the rate in males being almost four times that in females. The birth prevalence of both types of the deformity remained stable over the 15-year study period. The rate of caesarean and breech deliveries and the proportion of bilaterally affected feet was greater among infants with associated talipes equinovarus deformity. An accurate and complete identification of cases of isolated talipes equinovarus in the 1980-94 WA birth cohort provides a basis for furthering the understanding of the epidemiology and hence the aetiology of the deformity.

摘要

在西澳大利亚州(WA),马蹄内翻足是一种应报告的出生缺陷,自1980年以来,一直通过基于人群的出生缺陷登记处(BDR)进行确诊。马蹄内翻足畸形被分为两种不同且可区分的类型,即孤立性马蹄内翻足(不存在其他出生缺陷)和关联性马蹄内翻足(存在其他出生缺陷)。1980年至1994年期间,西澳大利亚州关联性马蹄内翻足的出生患病率为每1000例出生中有0.90例,孤立性马蹄内翻足的出生患病率为每1000例出生中有1.25例。原住民婴儿中孤立性畸形的发生率(每1000例出生中有3.49例)高于白种人婴儿(每1000例出生中有1.11例)和非原住民非白种人婴儿(每1000例出生中有0.73例)。孤立性畸形发生率的性别差异在原住民婴儿中最为显著,男性发生率几乎是女性的四倍。在15年的研究期间,两种类型畸形的出生患病率均保持稳定。关联性马蹄内翻足畸形婴儿的剖宫产和臀位分娩率以及双侧受累足部的比例更高。对1980 - 1994年西澳大利亚州出生队列中孤立性马蹄内翻足病例进行准确而完整的识别,为进一步了解该畸形的流行病学及病因学提供了基础。

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