Gelman S, Paz M, Levy E
Arch Surg. 1976 May;111(5):566-74. doi: 10.1001/archsurg.1976.01360230066014.
Thirty-eight starved cats, anesthetized with pentobarbital (Nembutal) sodium, received enteral administration of oxygen and other gases; the effect on intestinal motility as expressed by electrical activity was measured. Oxygen caused a notable increase in amplitude and frequency of slow electrical waves, while carbon dioxide and nitrogen caused no visible alterations. Phentolamine hydrochloride and propranolol hydrochloride together with atropine sulfate decreased the amplitude and frequency of oscillations to near zero; subsequent administration of enteral oxygen caused a notable increase in electrical activity, while enteral carbon dioxide produced no alterations. On the basis of our previous observations that enteral oxygen enhances oxygen and blood delivery to the gut wall, we suggest that the rise in stomach and intestinal electrical activity during enteral oxygen administration in conditions of surgical stress may be associated with an increase in oxygen and blood delivery to the gut wall.
38只饥饿的猫用戊巴比妥钠（速可眠）麻醉后，接受肠内氧气和其他气体给药；测量了电活动所表示的对肠道运动的影响。氧气使慢电波的振幅和频率显著增加，而二氧化碳和氮气未引起明显变化。盐酸酚妥拉明、盐酸普萘洛尔与硫酸阿托品一起使振荡的振幅和频率降低至接近零；随后肠内给予氧气使电活动显著增加，而肠内给予二氧化碳则无变化。基于我们之前的观察，即肠内氧气可增强氧气和血液向肠壁的输送，我们认为在手术应激情况下肠内给予氧气期间胃和肠道电活动的增加可能与氧气和血液向肠壁输送的增加有关。
