Viloria J E, Garcia J H
Beitr Pathol. 1976 Feb;157(1):14-22. doi: 10.1016/s0005-8165(76)80145-x.
Electron microscopic demonstration of herpes viral particles in cerebral tissues obtained at autopsy was easily accomplished. Analysis of the structural abnormalities in this case offers support for the proposed mechanisms of cellular injury in herpes simplex encephalitis. Interference with synthesis of nucleic acids and glycoproteins which has been suggested by in vitro studies correlates well with the structural abnormalities of endoplasmic reticulum cisternae and changes in nuclear membranes, described in the case reported herein.
在尸检时获取的脑组织中，通过电子显微镜很容易证实疱疹病毒颗粒的存在。对该病例结构异常的分析为单纯疱疹性脑炎中所提出的细胞损伤机制提供了支持。体外研究提示的核酸和糖蛋白合成受到干扰，与本文报道病例中所述的内质网池结构异常及核膜变化密切相关。
