从阿拉伯胶树中分离出一种具有抗炎活性的雄甾烯类固醇并进行X射线研究。
Isolation and X-ray study of an anti-inflammatory active androstene steroid from Acacia nilotica.
作者信息
Chaubal Rohini, Mujumdar A M, Puranik Vedavati G, Deshpande V H, Deshpande N R
出版信息
Planta Med. 2003 Mar;69(3):287-8. doi: 10.1055/s-2003-38482.
PMID:12677540
Abstract
3beta-Acetoxy-17beta-hydroxy-androst-5-ene was isolated from aerial parts of Acacia nilotica (L.) Willd (Mimosaceae). The structure of this compound was established by spectral analysis and single crystal X-ray diffraction analysis. The steroid showed dose-dependent anti-inflammatory activity against TPA-induced mouse earedema.
摘要
从阿拉伯胶树（含羞草科）的地上部分分离出了3β-乙酰氧基-17β-羟基-雄甾-5-烯。通过光谱分析和单晶X射线衍射分析确定了该化合物的结构。该甾体对佛波酯诱导的小鼠耳水肿表现出剂量依赖性抗炎活性。
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