Heys S D, Ogston K N
University of Aberdeen, Scotland, UK.
Int J Surg Investig. 2000;2(2):107-15.
Malnutrition continues to be a significant problem in patients undergoing surgery. The relationship between a poor nutritional status and subsequent post-operative morbidity and mortality is well recognised. It is logical, therefore, that malnourished patients should be given nutritional supplementation in the peri-operative period. However, the benefits of this approach have been debated and as we enter the new millennium there are many questions regarding then role of peri-operative nutritional support that remain unanswered.
This review aims to determine how we decide which patients are malnourished, which patients require nutritional support and what are the benefits, by what route (enteral or parenteral), and for how long should nuritional support be given are there key nutrients which should be given.
Nutritional status can be assessed routinely in all patients, with clear definitions of undernutrition, overnutrition and nutritional risk indices being applicable to surgical practice. Peri-operative parenteral nutritional support does benefit patients who are malnourished but they should receive at least 7 to 10 days of support before surgery. The theoretical benefits of enteral nutrition are clear but whether or not this translates into clinical benefits remains contentious. Nutritional support supplemented with key nutrients does seem to be advantageous by reducing the risk of septic post-operative complications and reducing overall stay in hospital.
Patients most likely to benefit from peri-operative nutritional support can be defined. Enteral nutritional support has advantages over parenteral nutrition and the administration of key nutrients has clinical benefits.
营养不良仍是手术患者面临的一个重大问题。营养状况不佳与术后发病率和死亡率之间的关系已得到充分认识。因此,合乎逻辑的是,营养不良的患者应在围手术期接受营养补充。然而,这种方法的益处一直存在争议,进入新千年后,关于围手术期营养支持的作用仍有许多问题未得到解答。
本综述旨在确定我们如何判定哪些患者营养不良,哪些患者需要营养支持,以及营养支持的益处是什么,通过何种途径(肠内或肠外)给予,应给予多长时间,是否有应给予的关键营养素。
所有患者的营养状况都可以进行常规评估,营养不良、营养过剩和营养风险指数的明确定义适用于外科手术实践。围手术期肠外营养支持确实对营养不良的患者有益,但他们应在手术前接受至少7至10天的支持。肠内营养的理论益处是明确的,但这是否能转化为临床益处仍存在争议。补充关键营养素的营养支持似乎有利于降低术后感染并发症的风险并缩短总体住院时间。
最有可能从围手术期营养支持中获益的患者可以被界定。肠内营养支持比肠外营养有优势,补充关键营养素具有临床益处。