Heberer M, Bodoky A, Babst R, Hörig H, Harder F
Dept. Chirurgie, Universitätsklinik Basel.
Schweiz Rundsch Med Prax. 1991 Nov 19;80(47):1303-11.
Parenteral and enteral nutrition are safe and efficacious substitutes of normal oral intake even for prolonged periods of time and offer adequate treatment of protein-calorie malnutrition and effective palliation of cancer cachexia. Perioperative nutritional support reduces operative morbidity and mortality in malnourished patients. Furthermore, parenteral and enteral nutrition are an effective primary treatment for acute inflammatory bowel disease, short bowel syndrome and small bowel fistulae. Enteral nutrients specifically support structure and function of both the intestinal mucosa and the mucosa-associated lymphatic tissues: Recent clinical data emphasize the need to feed enterally whenever possible, especially in critically ill patients. Continuing efforts to include new substrates and to create more balanced and disease-adapted solutions of parenteral and enteral nutrition will improve the available systems. In addition, parenteral and enteral nutrition as a component of new complex treatment modalities including growth factors and cytokines will improve treatment and patient care in general surgery, oncology and traumatology.
肠外营养和肠内营养即使在长时间内也是安全有效的正常口服摄入替代品,可充分治疗蛋白质 - 热量营养不良并有效缓解癌症恶病质。围手术期营养支持可降低营养不良患者的手术发病率和死亡率。此外,肠外营养和肠内营养是急性炎症性肠病、短肠综合征和小肠瘘的有效主要治疗方法。肠内营养物质特别支持肠黏膜和黏膜相关淋巴组织的结构和功能:最近的临床数据强调只要有可能就应进行肠内喂养,尤其是在危重病患者中。不断努力纳入新的底物并创造更平衡且适合疾病的肠外和肠内营养解决方案将改善现有体系。此外,肠外营养和肠内营养作为包括生长因子和细胞因子在内的新综合治疗模式的一部分,将改善普通外科、肿瘤学和创伤学的治疗及患者护理。