Strong J P, Richards M L
Atherosclerosis. 1976 May-Jun;23(3):451-76. doi: 10.1016/0021-9150(76)90007-1.
The association of cigarette smoking and atherosclerorosis was investigated in 1320 autopsied men, 25--64 years of age. Aortic and coronary lesions were evaluated visually in coded specimens and objectively by analysis of radiographs. Using schedules that had been tested on pairs of living persons, interviewers obtained estimates of cigarette smoking habits of the deceased men from surviving relatives. Data were analysed for black and white men in the total sample of cases and also in groups according to the presence (selected disease group) or absence (basal group) of diseases thought to be associated with smoking (emphysema, lung cancer, etc.) or with coronary heart disease (myocardial infarction, hypertension, diabetes, stroke, etc.). Atherosclerotic involvement of aorta and coronary arteries was greatest in heavy smokers and least in nonsmokers for both races in the total sample of cases, the basal group and the selected disease group.
在1320名年龄在25至64岁之间的男性尸体解剖中，研究了吸烟与动脉粥样硬化之间的关联。通过对编码标本进行肉眼评估，并通过X光片分析进行客观评估，来判断主动脉和冠状动脉病变情况。访谈人员使用在在世人群中经过测试的表格，从在世亲属那里获取了已故男性吸烟习惯的估计值。对整个病例样本中的黑人和白人男性数据进行了分析，同时也根据是否存在被认为与吸烟相关的疾病（肺气肿、肺癌等）或与冠心病相关的疾病（心肌梗死、高血压、糖尿病、中风等），将病例分为有相关疾病组（特定疾病组）和无相关疾病组（基础组）进行了分析。在整个病例样本、基础组和特定疾病组中，两个种族的重度吸烟者的主动脉和冠状动脉粥样硬化累及程度最高，不吸烟者最低。
