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[中国人肺癌危险因素的荟萃分析]

[Meta-analysis of the risk factors on lung cancer in Chinese people].

作者信息

Yao Hong-yan, Shi Lu-yuan

机构信息

Department of Epidemiology, Tongji Medical College, Huazhong Science and Technology University, Wuhan 430030, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2003 Jan;24(1):45-9.

Abstract

OBJECTIVE

To provide evidence for decision-making on lung cancer prevention through studying the main risk factors related to the incidence of lung cancer in Chinese people.

METHODS

The results from 41 epidemiological studies on risk factors of lung cancer from 1990 to 2001 were analyzed synthetically by Meta-analysis. The cumulative cases and controls were 5,600 and 6,892, respectively.

RESULTS

The pools odds ratio (OR) values of mentality (3.34), smoking (3.04), indoor coal pollution (3.20), indoor cooking oil fume pollution (2.72), family history of lung cancer (2.61), vegetables (0.49), fruits (0.69), BMI (1.57), family history of other tumour (2.97), personal history of respiratory system diseases (2.66), ventilation in kitchen (2.13), coal ever used in life (1.50), and exposure to environmental tobacco smoking (1.42).

CONCLUSION

The main factors influencing the incidence of lung cancer in Chinese people were patients, mentality, smoking, indoor environmental pollution, personal history of respiratory system diseases, family history of cancer, intake of vegetables, fruits and so on.

摘要

目的

通过研究与中国人群肺癌发病相关的主要危险因素,为肺癌预防决策提供依据。

方法

采用Meta分析综合分析1990年至2001年41项关于肺癌危险因素的流行病学研究结果。累积病例和对照分别为5600例和6892例。

结果

心理状态(3.34)、吸烟(3.04)、室内燃煤污染(3.20)、室内烹调油烟污染(2.72)、肺癌家族史(2.61)、蔬菜(0.49)、水果(0.69)、体重指数(1.57)、其他肿瘤家族史(2.97)、呼吸系统疾病个人史(2.66)、厨房通风(2.13)、生活中曾使用煤(1.50)以及接触环境烟草烟雾(1.42)的合并比值比(OR)值。

结论

影响中国人群肺癌发病的主要因素有患者、心理状态、吸烟、室内环境污染、呼吸系统疾病个人史、癌症家族史、蔬菜和水果摄入量等。

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