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The effect of simultaneous administration of levarterenol and phentolamine on renal blood flow.

作者信息

Cimmino V M, Bove E L, Argenta L C, Brown J W, Kirsh M M

出版信息

Ann Thorac Surg. 1976 Feb;21(2):158-63. doi: 10.1016/s0003-4975(10)64280-4.

Abstract

The effect of simultaneous administration of levarterenol and phentolamine upon renal blood flow was studied over a 3-hour period in 22 mongrel dogs. The infusion of levarterenol alone produced a fall in renal blood flow that ranged from 28 to 58% from the baseline value. When both drugs were administered simultaneously, renal flow fell only 17 to 22% from baseline (p less than 0.05). From these studies we conclude that the simultaneous administration of levarterenol and phentolamine in optimal ratios maintains renal blood flow near baseline levels.

摘要

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