Stanćák Andrej, Cohen Eric R, Seidler Rachael D, Duong Timothy Q, Kim Seong-Gi
Charles University Prague, Third Faculty of Medicine, Department of Normal, Pathological and Clinical Physiology, Prague, Czech Republic.
Cereb Cortex. 2003 May;13(5):475-85. doi: 10.1093/cercor/13.5.475.
Effects of the size of corpus callosum measured from in vivo magnetic resonance imaging (MRI) recordings on cortical activations evaluated using functional MRI (fMRI) were analyzed during motor tasks. Twelve right-handed men performed unilateral finger movements and bilateral movements either with or without a temporal delay between left and right fingers. The size of the rostral part of corpus callosum and the anterior and posterior callosal truncus explained 11.9 and 15.2% of activation in the mesial frontal cortex in unimanual left and right finger movements, respectively. In bimanual simultaneous movements, 34.2% of the activated voxels in the mesial frontal cortex were related to the size of corpus callosum. In bimanual movements in which left finger movement preceded the onset of the right finger movement, the callosal size accounted for 88.7% of activation in the mesial frontal cortex. In contrast, when the right finger movement preceded the left, callosal size accounted for only 31.3% of the mesial frontal cortex activation. The correlations between callosal parameters and activation over the lateral cortex were sparse and occurred only in bimanual movements. The results suggest that corpus callosum modulates the activity of the supplementary motor and cingulate cortical areas depending on temporal complexity of bimanual movements.
在运动任务期间，分析了从活体磁共振成像（MRI）记录测量的胼胝体大小对使用功能磁共振成像（fMRI）评估的皮质激活的影响。12名右利手男性进行单侧手指运动以及双侧运动，左右手指之间有或没有时间延迟。胼胝体嘴部以及胼胝体前后干的大小分别解释了单手左、右手手指运动中内侧额叶皮质激活的11.9%和15.2%。在双手同时运动中，内侧额叶皮质中34.2%的激活体素与胼胝体大小有关。在左手手指运动先于右手手指运动开始的双手运动中，胼胝体大小占内侧额叶皮质激活的88.7%。相反，当右手手指运动先于左手时，胼胝体大小仅占内侧额叶皮质激活的31.3%。胼胝体参数与外侧皮质激活之间的相关性较少，且仅发生在双手运动中。结果表明，胼胝体根据双手运动的时间复杂性调节辅助运动区和扣带皮质区域的活动。
