Shafik A, Ahmed I, El-Sibai O, Mostafa R M
Department of Surgery, Faculty of Medicine, Cairo University, Egypt.
Eur Surg Res. 2003 Mar-Apr;35(2):103-7. doi: 10.1159/000069399.
BACKGROUND/AIMS: To assess the results of peripheral neuromodulation for the treatment of fecal incontinence (FI) resulting from uninhibited rectal contraction (URC) or uninhibited anal sphincter relaxation (UASR).
The work comprised 32 patients (age 38.2 +/- 6.7 years; 22 women) with FI in whom conventional therapy had failed before enrollment in the study. Twenty-six had URC and 6 UASR. Peripheral neurostimulation was effected by posterior tibial nerve stimulation using a Stoller Afferent Nerve Stimulator (UroSurge, Coralville, lowa, USA). The needle was introduced into the skin cephalad to the medial malleolus. Stimulation (parameters: 0.5-10 mA, 200 micros, 20 Hz) was performed every other day for 4 weeks. Functional assessment was done by a questionnaire (incontinence score: 0-20) and physiologic studies.
Group 1: 17 patients (13 URC, 4 UASR) had FI improvement, recording a mean score of 1.7 of 20. Group 2: 10 patients (8 URC, 2 UASR) had fair improvement (score 8.6). Group 3: 5 patients had poor results (score 14.8). Rectometric recording showed improvement in groups 1 and 2. Recurrence of symptoms occurred in 8 patients; 6 improved after retreatment.
A percutaneous access to the S(3) spinal region was achieved through the posterior tibial nerve. Improvement of FI was achieved in 78.2%. The technique is simple, easy, without complications and cost-effective. It can be done as an outpatient procedure or by the patient at home. The results need to be reproduced on a large number of patients.
背景/目的:评估外周神经调节治疗因直肠无抑制性收缩(URC)或肛门括约肌无抑制性松弛(UASR)导致的大便失禁(FI)的效果。
该研究纳入32例FI患者(年龄38.2±6.7岁;22例女性),这些患者在入组研究前常规治疗均失败。其中26例有URC,6例有UASR。使用Stoller传入神经刺激器(美国爱荷华州珊瑚维尔市UroSurge公司)通过胫后神经刺激进行外周神经刺激。将针经皮刺入内踝上方的皮肤。每隔一天进行刺激(参数:0.5 - 10 mA,200微秒,20 Hz),持续4周。通过问卷调查(失禁评分:0 - 20)和生理研究进行功能评估。
第1组:17例患者(13例URC,4例UASR)的FI症状改善,20分制的平均评分为1.7分。第2组:10例患者(8例URC,2例UASR)有较好改善(评分8.6分)。第3组:5例患者效果较差(评分14.8分)。直肠测压显示第1组和第2组有改善。8例患者症状复发;6例经再次治疗后改善。
通过胫后神经实现了经皮进入S(3)脊髓区域。78.2%的患者FI症状得到改善。该技术简单、易行,无并发症且成本效益高。可作为门诊手术或由患者在家中进行。结果需要在大量患者中重复验证。