Department of Gastrointestinal Surgery, Vall d'Hebron Hospital, Barcelona, Spain.
Colorectal Unit, Aldo Moro University Bari, Bari, Italy.
Tech Coloproctol. 2018 Nov;22(11):875-879. doi: 10.1007/s10151-018-1892-0. Epub 2018 Dec 18.
Fecal incontinence (FI) is a multifactorial disease that affects patients' quality of life. The aim of this study was to evaluate the efficacy of posterior tibial nerve stimulation (PTNS) in the treatment of FI and to assess the medium-term results.
A prospective cohort of patients with FI treated with PTNS between 2012 and 2014 was analysed. Endoluminal ultrasound and anorectal physiologic studies were performed in all patients. The efficacy of PTNS was assessed using a validated questionnaire (Cleveland Clinic Incontinence Score) at baseline, after treatment, and 2 years later. The Vaizey score was also used at 2-year follow-up to assess urge incontinence.
Fifty-six patients (38 females; mean age 59.7 years) with FI were treated. The causes of FI were mainly obstetric injury and previous colorectal surgery. A decrease of 50% from baseline CCIS was seen in 41.1% of patients after PTNS. One-third maintained a minimum of 50% decrease of their initial CCIS after 2 years. Comparing CCIS at baseline, after treatment, and at 2-year follow-up, a statistically significant difference was observed (p < 0.0001 and p < 0.0004 respectively). Medium-term improvement was not maintained in patients with passive and mixed FI, while it was maintained in those with urge incontinence. At 2 years, patients with mild incontinence maintained the greatest response.
PTNS is a safe, effective, non-invasive treatment for FI with good results in almost half of the patients at the end of the treatment. There is also an acceptable maintained response at 2-year follow-up. It seems to be most successful in patients with mild incontinence and urge incontinence.
粪便失禁(FI)是一种多因素疾病,影响患者的生活质量。本研究旨在评估经皮胫后神经刺激(PTNS)治疗 FI 的疗效,并评估其中期结果。
对 2012 年至 2014 年间接受 PTNS 治疗的 FI 患者进行前瞻性队列研究。所有患者均进行腔内超声和肛肠生理研究。在基线、治疗后和 2 年后使用经过验证的问卷(克利夫兰诊所失禁评分)评估 PTNS 的疗效。在 2 年随访时还使用 Vaizey 评分评估急迫性失禁。
56 例 FI 患者(38 例女性;平均年龄 59.7 岁)接受了治疗。FI 的病因主要为产科损伤和既往结直肠手术。PTNS 后,41.1%的患者 CCIS 降低 50%。三分之一的患者在 2 年后仍保持 CCIS 初始值降低至少 50%。与基线、治疗后和 2 年随访时的 CCIS 相比,差异均有统计学意义(p<0.0001 和 p<0.0004)。被动性和混合性 FI 患者的中期改善无法维持,而急迫性失禁患者的改善可维持。2 年后,轻度失禁患者保持最大的反应。
PTNS 是 FI 的一种安全、有效、非侵入性的治疗方法,在治疗结束时几乎有一半的患者效果良好。在 2 年随访时,也有可接受的维持反应。它似乎在轻度失禁和急迫性失禁患者中最成功。