原发性胆汁性肝硬化与溃疡性结肠炎：一例病例报告及文献综述
Primary biliary cirrhosis and ulcerative colitis: a case report and review of literature.
作者信息
Xiao Wen-Bin, Liu Yu-Lan
机构信息
Department of Gastroenterology, People's Hospital, Peking University, Beijing 100044, China.
出版信息
World J Gastroenterol. 2003 Apr;9(4):878-80. doi: 10.3748/wjg.v9.i4.878.
AIM
To summarize the characteristics of patients suffered from primary biliary cirrhosis associated with ulcerative colitis.
METHODS
To report a new case and review the literature.
RESULTS
There were 18 cases (including our case) of primary biliary cirrhosis complicated with ulcerative colitis reported in the literature. Compared with classical primary biliary cirrhosis, the patients were more often males and younger similar. The bowel lesions were usually mild with proctitis predominated. While ulcerative colitis was diagnosed before primary biliary cirrhosis in 13 cases, the presentation of primary biliary cirrhosis was earlier than that of ulcerative colitis in our new case reported here. The prevalence of primary biliary cirrhosis among patients of ulcerative colitis was almost 30 times higher than in general population.
CONCLUSION
Association of primary biliary cirrhosis with ulcerative colitis is rare. It should be considered in the differential diagnosis of hepatobiliary disease in patients with ulcerative colitis, and vice versa.
目的
总结原发性胆汁性肝硬化合并溃疡性结肠炎患者的特征。
方法
报告1例新病例并复习文献。
结果
文献报道了18例（包括我们的病例）原发性胆汁性肝硬化合并溃疡性结肠炎。与典型的原发性胆汁性肝硬化相比，这些患者男性更多，年龄相近。肠道病变通常较轻，以直肠炎为主。13例患者溃疡性结肠炎在原发性胆汁性肝硬化之前被诊断，而在我们报道的新病例中，原发性胆汁性肝硬化的表现早于溃疡性结肠炎。溃疡性结肠炎患者中原发性胆汁性肝硬化的患病率几乎是普通人群的30倍。
结论
原发性胆汁性肝硬化与溃疡性结肠炎的关联罕见。在溃疡性结肠炎患者的肝胆疾病鉴别诊断中应考虑到这种情况，反之亦然。
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