Nakayama M, Tsuji H, Shimono J, Azuma K, Ogata H, Matsumoto T, Aoyagi K, Fujishima M, Iida M
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
Fukuoka Igaku Zasshi. 2001 Oct;92(10):354-9.
A rare case of concurrent primary biliary cirrhosis and ulcerative colitis is described in a 61 year-old Japanese male. Primary biliary cirrhosis was diagnosed on the basis of characteristic histologic findings and a positive serum mitochondrial antibody test. Ulcerative colitis was diagnosed from typical findings on colonoscopy and the histologic features of a sigmoid colon biopsy specimen. This is the 12th report of a patient presenting with the combination of primary biliary cirrhosis and ulcerative colitis. The potential autoimmune relationships on the basis of these conditions are discussed.
本文描述了一例61岁日本男性同时患有原发性胆汁性肝硬化和溃疡性结肠炎的罕见病例。原发性胆汁性肝硬化是根据特征性组织学表现和血清线粒体抗体试验阳性诊断的。溃疡性结肠炎是通过结肠镜检查的典型表现和乙状结肠活检标本的组织学特征诊断的。这是第12例报告的同时患有原发性胆汁性肝硬化和溃疡性结肠炎的患者。本文还讨论了基于这些病症的潜在自身免疫关系。