Ribeiro G G
Br J Cancer. 1976 Apr;33(4):465-7. doi: 10.1038/bjc.1976.72.
A retrospective survey has been made of 58 patients with recurrent and advanced male breast cancer treated with oral diethylstilboestrol. Fifty-five patients were suitable for assessment. Fourteen patients had an objective response and 7 had a partial response giving a total response of 21/55 patients (38%). The median remission for the objective responders was 7 years. Three patients are alive and free of disease; one has now been in remission for 13 years. It is suggested that diethylstilboestrol is a useful treatment in patients with soft tissue disease (breast, chest wall and/or lymph nodes).
对58例复发性和晚期男性乳腺癌患者采用口服己烯雌酚进行了回顾性调查。55例患者适合评估。14例患者有客观缓解,7例部分缓解,55例患者中共有21例缓解(38%)。客观缓解者的中位缓解期为7年。3例患者存活且无疾病;1例现已缓解13年。提示己烯雌酚对软组织疾病(乳房、胸壁和/或淋巴结)患者是一种有效的治疗方法。