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Membrane-bound heat shock protein 70 (Hsp70) in acute myeloid leukemia: a tumor specific recognition structure for the cytolytic activity of autologous NK cells.

作者信息

Gehrmann Mathias, Schmetzer Helga, Eissner Günther, Haferlach Torsten, Hiddemann Wolfgang, Multhoff Gabriele

出版信息

Haematologica. 2003 Apr;88(4):474-6.

PMID:12681978
Abstract
摘要

相似文献

1
Membrane-bound heat shock protein 70 (Hsp70) in acute myeloid leukemia: a tumor specific recognition structure for the cytolytic activity of autologous NK cells.急性髓系白血病中的膜结合热休克蛋白70（Hsp70）：一种针对自体自然杀伤细胞细胞溶解活性的肿瘤特异性识别结构。
Haematologica. 2003 Apr;88(4):474-6.
2
Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells.膜结合型热休克蛋白70（Hsp70）、Bag-4和Hsp40的双重功能：抵御辐射诱导效应及作为自然杀伤细胞的靶结构
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3
Treatment of colon and lung cancer patients with ex vivo heat shock protein 70-peptide-activated, autologous natural killer cells: a clinical phase i trial.用体外热休克蛋白70-肽激活的自体自然杀伤细胞治疗结肠癌和肺癌患者：一项I期临床试验。
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An Hsp70 peptide initiates NK cell killing of leukemic blasts after stem cell transplantation.一种热休克蛋白70（Hsp70）肽在干细胞移植后启动自然杀伤细胞对白血病原始细胞的杀伤作用。
Leuk Res. 2008 Apr;32(4):527-34. doi: 10.1016/j.leukres.2007.03.027. Epub 2007 May 31.
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Immunostimulatory functions of membrane-bound and exported heat shock protein 70.膜结合型和分泌型热休克蛋白70的免疫刺激功能
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6
A 14-mer Hsp70 peptide stimulates natural killer (NK) cell activity.一种14聚体热休克蛋白70肽可刺激自然杀伤（NK）细胞活性。
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A 14-mer peptide from HSP70 protein is the critical epitope which enhances NK activity against tumor cells in vivo.热休克蛋白70（HSP70）蛋白的一个14肽是增强自然杀伤细胞（NK）在体内抗肿瘤细胞活性的关键表位。
Immunol Invest. 2007;36(3):233-46. doi: 10.1080/08820130600992073.
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Activation of natural killer cells by heat shock protein 70.热休克蛋白70对自然杀伤细胞的激活作用。
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Mechanism of interaction between 70-kd heat shock proteins and rat CD3+, 4-, 8- killer T cells--implication in tumor rejection activity.70-kd热休克蛋白与大鼠CD3 +、4 -、8 -杀伤性T细胞之间的相互作用机制——对肿瘤排斥活性的影响
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Heat shock protein 70 (Hsp70): membrane location, export and immunological relevance.热休克蛋白70（Hsp70）：膜定位、输出及免疫学相关性
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Biomolecules. 2023 May 22;13(5):874. doi: 10.3390/biom13050874.
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Is It Still Possible to Think about HSP70 as a Therapeutic Target in Onco-Hematological Diseases?在血液肿瘤疾病中，HSP70 仍然可以作为治疗靶点吗？
Biomolecules. 2023 Mar 28;13(4):604. doi: 10.3390/biom13040604.
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Clinicopathological significance of HSP70 expression in gastric cancer: a systematic review and meta-analysis.
胃癌中 HSP70 表达的临床病理意义：系统评价和荟萃分析。
BMC Gastroenterol. 2021 Nov 22;21(1):437. doi: 10.1186/s12876-021-01990-4.
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Hsp70 Interacts with the TREM-1 Receptor Expressed on Monocytes and Thereby Stimulates Generation of Cytotoxic Lymphocytes Active against MHC-Negative Tumor Cells.热休克蛋白 70（Hsp70）与单核细胞表面表达的 TREM-1 受体相互作用，从而刺激针对 MHC 阴性肿瘤细胞的细胞毒性淋巴细胞的产生。
Int J Mol Sci. 2021 Jun 26;22(13):6889. doi: 10.3390/ijms22136889.
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Cells. 2020 May 20;9(5):1263. doi: 10.3390/cells9051263.
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HSP70/IL-2 Treated NK Cells Effectively Cross the Blood Brain Barrier and Target Tumor Cells in a Rat Model of Induced Glioblastoma Multiforme (GBM).HSP70/IL-2 处理的 NK 细胞可有效穿透血脑屏障，并在诱导性多形性胶质母细胞瘤（GBM）大鼠模型中靶向肿瘤细胞。
Int J Mol Sci. 2020 Mar 25;21(7):2263. doi: 10.3390/ijms21072263.
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Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance.自然杀伤细胞对化疗应激癌细胞的反应：在肿瘤免疫监视中的作用。
Front Immunol. 2017 Sep 25;8:1194. doi: 10.3389/fimmu.2017.01194. eCollection 2017.
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B-Cell-Based and Soluble Biomarkers in Body Liquids for Predicting Acute/Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.用于预测异基因造血干细胞移植后急性/慢性移植物抗宿主病的体液中基于B细胞的可溶性生物标志物
Front Immunol. 2017 Jan 16;7:660. doi: 10.3389/fimmu.2016.00660. eCollection 2016.
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Cancers (Basel). 2016 Jan 13;8(1):15. doi: 10.3390/cancers8010015.