Meyer L, Gharib M, Lerable J, Sarr A, Boufassa F, Deveau C, Boucherit S, Chaib A, Hubert J-B, Persoz A, Delfraissy J-F, Rouzioux C
Service d'Epidémiologie, INSERM U569, Hôpital de Bicêtre AP/HP, 82, rue du Général-Leclerc, 94276 Le Kremlin-Bicêtre Cedex.
Rev Epidemiol Sante Publique. 2003 Feb;51(1 Pt 2):151-8.
The French SEROCO and HEMOCO hospital-based cohorts have enrolled and followed HIV-infected patients, before and after the highly active antiretroviral therapy era. Among the objectives in 1988, was explicitly mentioned the constitution of a centralised bank of biological material (serums at enrollment and every 6 months, PBMC at enrollment and every 18 months). This paper details the organisation of the bank and the numerous studies performed from this bank, and presents a few simple decision rules which have been developed with the growing acquired experience.
法国基于医院的SEROCO和HEMOCO队列在高效抗逆转录病毒治疗时代之前和之后纳入并随访了HIV感染患者。1988年的目标中明确提到要建立一个生物材料中央库（入组时及每6个月采集血清，入组时及每18个月采集外周血单核细胞）。本文详细介绍了该库的组织情况以及从该库开展的众多研究，并给出了一些随着经验积累而制定的简单决策规则。
