Biederman J, Spencer T
Pediatric Psychopharmacology Unit, Child Psychiatry Service, Massachusetts General Hospital, Boston 02114, USA.
J Atten Disord. 2002;6 Suppl 1:S101-7. doi: 10.1177/070674370200601s12.
Attention-Deficit/Hyperactivity Disorder (ADHD) can persist into adulthood with a continuation of the pattern of childhood psychopathology, cognition and functioning. Adult comorbidities include substance use disorders, antisocial personality disorder, anxiety, and depression. Studies have shown that as in children, methylphenidate treatment for adults can lead to a robust, dose-dependent improvement in ADHD symptoms. Future research is needed to evaluate the safety and efficacy of long-term treatment with methylphenidate (MPH).
注意力缺陷多动障碍(ADHD)可延续至成年期,童年期的精神病理学、认知及功能模式持续存在。成人共病包括物质使用障碍、反社会人格障碍、焦虑症和抑郁症。研究表明,与儿童一样,哌甲酯治疗成人ADHD可带来显著的、剂量依赖性的症状改善。需要进一步研究来评估哌甲酯(MPH)长期治疗的安全性和有效性。