撒哈拉以南非洲农村地区癫痫患者的功能状况。

The functional status of people with epilepsy in rural sub-Saharan Africa.

作者信息

Birbeck Gretchen L, Kalichi Ellie M N

机构信息

Michigan State University, #138 Service Road, A217, East Lansing, MI 48824-1313, USA.

出版信息

J Neurol Sci. 2003 May 15;209(1-2):65-8. doi: 10.1016/s0022-510x(02)00467-7.

DOI:10.1016/s0022-510x(02)00467-7

PMID:12686404

Abstract

PURPOSE

Little data is available regarding the impact of epilepsy on the functional status of people with epilepsy (PWE) in developing countries. In sub-Saharan Africa, limited medical services and social stigmatization subject PWE to substantial physical, psychological and social deprivation. To better delineate the overall burden and distribution of epilepsy-associated disability in sub-Saharan Africa, we assessed the functional status of PWE in a rural, population-based sample and made comparisons to published reports from urban Zimbabwe.

METHODS

A population-based survey of PWE with epilepsy in rural Zambia utilizing WHO questionnaires.

RESULTS

Among 86 PWE in 3 rural Zambian communities, 67% participated in the interviews. Only 62% of PWE were receiving treatment. Five to seven percent of rural PWE reported problems with basic hygiene and 9-14% were unable to fulfill work demands, attend social events or enjoy leisure activities. In contrast, 95% of urban PWE denied any problems with social functioning, work performance or relationships. Compared to the urban population, rural PWE had a greater seizure burden (2.3/month vs. 1/month, p=0.007) and reported more difficulties with activities of daily living, including problem solving (70% vs. 54%, p=0.02), speed of thinking (70% vs. 59%, p=0.02) and relationships with co-workers (68% vs. 26%, p< or =0.005).

CONCLUSIONS

A significant proportion of PWE in rural sub-Saharan Africa report problems fulfilling both social and professional functions. These results also suggest that rural PWE may have poorer functional status than their urban counterparts.

摘要

目的

关于癫痫对发展中国家癫痫患者功能状况的影响，现有数据较少。在撒哈拉以南非洲，有限的医疗服务和社会污名化使癫痫患者在身体、心理和社会方面遭受严重剥夺。为了更好地描述撒哈拉以南非洲癫痫相关残疾的总体负担和分布情况，我们在一个基于农村人口的样本中评估了癫痫患者的功能状况，并与津巴布韦城市地区已发表的报告进行了比较。

方法

利用世界卫生组织的问卷对赞比亚农村地区的癫痫患者进行基于人群的调查。

结果

在赞比亚农村3个社区的86名癫痫患者中，67%参与了访谈。只有62%的癫痫患者正在接受治疗。5%至7%的农村癫痫患者报告存在基本卫生问题，9%至14%的患者无法满足工作需求、参加社交活动或享受休闲活动。相比之下，95%的城市癫痫患者否认在社交功能、工作表现或人际关系方面存在任何问题。与城市人口相比，农村癫痫患者的癫痫发作负担更重（每月2.3次 vs. 每月1次，p = 0.007），并且在日常生活活动方面报告了更多困难，包括解决问题（70% vs. 54%，p = 0.02）、思维速度（70% vs. 59%，p = 0.02）以及与同事的关系（68% vs. 26%，p≤0.005）。