人阔筋膜在兔阴道模型中植入后拉伸强度的变化。
Changes in tensile strength of cadaveric human fascia lata after implantation in a rabbit vagina model.
作者信息
Walter Andrew J, Morse Abraham N, Leslie Kevin O, Zobitz Mark E, Hentz Joseph G, Cornella Jeffrey L
机构信息
Division of Urogynecology, Department of Laboratory Medicine, Mayo Clinic, Scottsdale, AZ, USA.
出版信息
J Urol. 2003 May;169(5):1907-10; discussion 1910. doi: 10.1097/01.ju.0000061182.21353.a5.
PURPOSE
We determined changes in tensile properties after vaginal implantation of human cadaveric fascia lata.
MATERIALS AND METHODS
Baseline tensile properties were determined for freeze-dried, gamma irradiated human cadaveric fascia lata from 3 separate lots. Fascial strips (2 x 0.5 cm.) from 2 lots were implanted between the rectovaginal membrane and vaginal mucosa in New Zealand white rabbits. The strips were excised en bloc 12 weeks after implantation. Tensile property measurements were repeated and compared with pre-implantation values.
RESULTS
Pre-implantation interlot and intralot variability in baseline tensile properties was significant. After implantation there was an approximate 90% decrease in tensile strength from baseline values. There was no gross evidence of graft autolysis.
CONCLUSIONS
The decrease in tensile strength of cadaveric fascial graft was significant after implantation in this model.
目的
我们测定了人尸体阔筋膜阴道植入后拉伸性能的变化。
材料与方法
对来自3个不同批次的冻干、γ射线辐照的人尸体阔筋膜测定基线拉伸性能。从2个批次中取出筋膜条（2×0.5厘米）植入新西兰白兔的直肠阴道膜和阴道黏膜之间。植入12周后将筋膜条整块切除。重复进行拉伸性能测量并与植入前的值进行比较。
结果
植入前不同批次和同批次内基线拉伸性能的变异性显著。植入后，拉伸强度相对于基线值下降了约90%。没有明显的移植物自溶迹象。
结论
在此模型中，尸体筋膜移植物植入后拉伸强度显著下降。
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