Cerè Vanda, Pollicino Salvatore, Ricci Alfredo
Department of Organic Chemistry, A. Mangini University of Bologna, Viale Risorgimento 4, I-40136 Bologna, Italy.
J Org Chem. 2003 Apr 18;68(8):3311-4. doi: 10.1021/jo020511z.
The enantioselective synthesis of bicyclic sulfonium salts 8 or 9, thioanalogues of swainsonine derivatives, is described. The synthetic strategy is based on a stereo- and regiospecific transannular cyclization reaction of nine-membered cyclic sulfides, mediated by Me(3)SiI or carried out under acidic catalysis.
本文描述了双环硫鎓盐8或9（苦马豆素衍生物的硫类似物）的对映选择性合成。合成策略基于由Me(3)SiI介导或在酸性催化下进行的九元环硫化物的立体和区域特异性跨环环化反应。
