对映体纯双环锍盐的新合成方法：苦马豆素类似物。
New synthetic approach to enantiopure bicyclic sulfonium salts: swainsonine analogues.
作者信息
Cerè Vanda, Pollicino Salvatore, Ricci Alfredo
机构信息
Department of Organic Chemistry, A. Mangini University of Bologna, Viale Risorgimento 4, I-40136 Bologna, Italy.
出版信息
J Org Chem. 2003 Apr 18;68(8):3311-4. doi: 10.1021/jo020511z.
PMID:12688809
Abstract
The enantioselective synthesis of bicyclic sulfonium salts 8 or 9, thioanalogues of swainsonine derivatives, is described. The synthetic strategy is based on a stereo- and regiospecific transannular cyclization reaction of nine-membered cyclic sulfides, mediated by Me(3)SiI or carried out under acidic catalysis.
摘要
本文描述了双环硫鎓盐8或9（苦马豆素衍生物的硫类似物）的对映选择性合成。合成策略基于由Me(3)SiI介导或在酸性催化下进行的九元环硫化物的立体和区域特异性跨环环化反应。
Zotero 插件