Lemak Alexander S, Lepock James R, Chen Jeff Z Y
Department of Physics, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.
Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Mar;67(3 Pt 1):031910. doi: 10.1103/PhysRevE.67.031910. Epub 2003 Mar 19.
A protein molecule under the stress of an external denaturing force acting on a terminal end or on the entire molecule is expected to unfold, possibly through a few intermediate stages depending on the magnitude of the denaturing force. We have investigated two protein minimal models under various types of denaturing force fields using the collision molecular-dynamics simulation, in order to critically examine the relationship between the folding pathways observed in different protein denaturing experiments.
