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本文引用的文献

1
Encouraging HIV testing in GUM clinics--can we dispense with the pre-test discussion? Genitourinary Medicine.在性传播疾病诊所鼓励进行HIV检测——我们能否省去检测前的讨论?《性传播疾病医学》
Int J STD AIDS. 1999 Nov;10(11):728-9. doi: 10.1258/0956462991913411.
2
Role of type specific herpes simplex virus serology in the diagnosis and management of genital herpes.特定型单纯疱疹病毒血清学在生殖器疱疹诊断和管理中的作用。
Sex Transm Infect. 1998 Jun;74(3):175-8. doi: 10.1136/sti.74.3.175.
3
Type-specific serological testing for herpes simplex infection.单纯疱疹感染的型特异性血清学检测。
Int J STD AIDS. 1998 Sep;9(9):497-500. doi: 10.1258/0956462981922674.
4
Patient attitudes to type specific serological tests in the diagnosis of genital herpes.患者对特定类型血清学检测在生殖器疱疹诊断中的态度。
Genitourin Med. 1997 Aug;73(4):259-62. doi: 10.1136/sti.73.4.259.
5
HSV type specific antibody tests: patients are ready, are clinicians?单纯疱疹病毒分型特异性抗体检测:患者已准备好,临床医生呢?
Genitourin Med. 1997 Aug;73(4):235-6. doi: 10.1136/sti.73.4.235.
6
Antenatal serum screening for genital herpes: a study of knowledge and attitudes of women at a central London hospital.产前血清生殖器疱疹筛查:伦敦市中心一家医院女性的知识与态度研究
Br J Obstet Gynaecol. 1997 Mar;104(3):347-9. doi: 10.1111/j.1471-0528.1997.tb11466.x.
7
Risk of acquisition of genital herpes simplex virus type 2 in sex partners of persons with genital herpes: a prospective couple study.生殖器疱疹患者性伴侣感染2型单纯疱疹病毒的风险:一项前瞻性伴侣研究。
J Infect Dis. 1993 Apr;167(4):942-6. doi: 10.1093/infdis/167.4.942.
8
Antibody to herpes simplex virus type 2 as serological marker of sexual lifestyle in populations.2型单纯疱疹病毒抗体作为人群性生活方式的血清学标志物。
BMJ. 1994 Nov 19;309(6965):1325-9. doi: 10.1136/bmj.309.6965.1325.
9
Virologic characteristics of subclinical and symptomatic genital herpes infections.亚临床和有症状生殖器疱疹感染的病毒学特征
N Engl J Med. 1995 Sep 21;333(12):770-5. doi: 10.1056/NEJM199509213331205.
10
Screening to detect asymptomatic shedding of herpes simplex virus (HSV) in women with recurrent genital HSV infection.对复发性生殖器单纯疱疹病毒(HSV)感染的女性进行筛查,以检测无症状的HSV脱落情况。
Genitourin Med. 1986 Jun;62(3):181-5. doi: 10.1136/sti.62.3.181.

在英国一家性传播疾病诊所引入特定类型疱疹抗体筛查试验的可接受性。

The acceptability of the introduction of a type specific herpes antibody screening test into a genitourinary medicine clinic in the United Kingdom.

作者信息

Mullan H M, Munday P E

机构信息

Department of Genitourinary Medicine, Watford General Hospital, Watford, Herts, UK.

出版信息

Sex Transm Infect. 2003 Apr;79(2):129-33. doi: 10.1136/sti.79.2.129.

DOI:10.1136/sti.79.2.129
PMID:12690134
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1744615/
Abstract

OBJECTIVE

To determine the uptake of a type specific herpes simplex antibody test if it were offered as part of routine screening in a genitourinary medicine clinic in a district general hospital in the United Kingdom.

METHODS

Stage 1. A series of 207 consecutive new attenders and 205 patients who had attended the clinic previously were given written information about the test and asked whether they would want to have the test if it were available. They were asked whether they would wish to discuss it further with a counsellor before making a decision. Stage 2. Another series of 434 consecutive patients were offered the test after reading an information leaflet detailing the advantages and disadvantages of being tested. They were also offered the opportunity to see a counsellor for further information.

RESULTS

In stage 1 of the study, 51% of men and 54% of women said they would want the test if it were available. 32% of men and 40% of women requested counselling. In stage 2, when the test was offered, 41% of men and 37% of women chose to have it, and 23% of men and 7% of women requested further information from the counsellor. 20 patients were herpes simplex virus type 2 (HSV-2) positive-four of whom would have been diagnosed on clinical grounds at the time of presentation. A further 12 men and 20 women excluded themselves from the study because they were known to have genital herpes. Therefore, type specific serology contributed 30% to total diagnoses in this population-16 out of a population of 52 would have remained undiagnosed without having had the test.

CONCLUSION

In this population, the uptake of the type specific herpes simplex antibody test was much less than expected and screening was of limited benefit in identifying large numbers of previously unrecognised HSV-2 positive patients.

摘要

目的

确定在英国一家地区综合医院的泌尿生殖医学诊所,将特定类型的单纯疱疹抗体检测作为常规筛查的一部分时,其接受程度。

方法

第一阶段。向连续就诊的207名新患者以及之前在该诊所就诊过的205名患者提供有关该检测的书面信息,并询问如果有该检测,他们是否愿意进行检测。还询问他们在做出决定之前是否希望与咨询师进一步讨论。第二阶段。在阅读了一份详细说明检测利弊的信息传单后,向另外连续的434名患者提供该检测。他们也有机会咨询咨询师以获取更多信息。

结果

在研究的第一阶段,51%的男性和54%的女性表示如果有该检测,他们愿意进行检测。32%的男性和40%的女性要求咨询。在第二阶段,当提供该检测时,41%的男性和37%的女性选择进行检测,23%的男性和7%的女性要求咨询师提供更多信息。20名患者为单纯疱疹病毒2型(HSV - 2)阳性,其中4名在就诊时可根据临床症状诊断。另有12名男性和20名女性因已知患有生殖器疱疹而退出研究。因此,特定类型的血清学检测在该人群的总诊断中占30%,在52人的人群中,如果没有进行该检测,16人将仍未被诊断。

结论

在该人群中,特定类型的单纯疱疹抗体检测的接受程度远低于预期,筛查在识别大量先前未被识别的HSV - 2阳性患者方面益处有限。