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[黄疸患者的缓慢注射胆管造影术。犬的实验研究]

[Slow infusion cholangiography in jaundice. An experimental study in the dog].

作者信息

Burgener F A, Fischer H W

出版信息

Rofo. 1975 Feb;122(2):145-8. doi: 10.1055/s-0029-1230041.

Abstract

56 intravenous cholangiograms were performed in eleven dogs with either advanced hepatic damage or complete common bile duct obstruction. If radiographic visualization of the biliary system did not occur within 8 hours after a 30 minute infusion with 0.6 ml/kg iodipamide 52%, the result could not be improved by just extending the infusion time to 2 and 6 hours. However, a slight improvement was obtained, when the iodipamide dose was increased up to 1.8 ml/kg. Nevertheless we do not recommend a massive increase of the dose in the icteric patient, because it is likely that the risk of toxic side effects increases with an increasing iodipamide dose.

摘要

对11只患有晚期肝损伤或完全性胆总管梗阻的犬进行了56次静脉胆管造影。如果在以0.6 ml/kg的52%碘番酸输注30分钟后8小时内未出现胆道系统的X线显影,则仅将输注时间延长至2小时和6小时并不能改善结果。然而,当碘番酸剂量增加至1.8 ml/kg时,情况稍有改善。尽管如此,我们不建议黄疸患者大量增加剂量,因为随着碘番酸剂量的增加,出现毒性副作用的风险可能会增加。

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