Younes S, Chebel S, Boukhris S, Frih-Ayed M
Service de Neurologie, EPS Fattouma Bourguiba de Monastir, 5000 Monastir, Tunisie.
Rev Neurol (Paris). 2002 Dec;158(12 Pt 1):1202-4.
Central nervous system involvement in patients with hepatitis C infection have been rarely reported. Stroke and encephalopathic syndromes have been frequently attributed to the ischemia or hemorrhage associated with mixed cryoglobulinemia and anticardiolipin antibodies. We describe the case of a 31-year-old woman with cerebral ischemia who had hepatitis C infection confirmed by polymerase change reaction detection of HCV RNA but who was negative for cryoglobulinemia. Cerebral involvement may be the initial manifestation of hepatitis C infection.
丙型肝炎感染患者中枢神经系统受累的情况鲜有报道。中风和脑病综合征常归因于与混合性冷球蛋白血症及抗心磷脂抗体相关的缺血或出血。我们描述了一名31岁患脑缺血的女性病例，该患者通过聚合酶链反应检测HCV RNA确诊为丙型肝炎感染，但冷球蛋白血症检测呈阴性。脑部受累可能是丙型肝炎感染的初始表现。
