Bourassa M G, Cantin M, Sandborn E B, Pederson E
Circulation. 1976 Jun;53(6):992-6. doi: 10.1161/01.cir.53.6.992.
Following routine coronary arteriography, surface irregularities and thrombogenesis of the inner and outer wall of six Ducor polyurethane and six RPX polyethylene coronary catheters were studied by scanning electron microscopy. Polyurethane catheters had rough and highly irregular external and internal surfaces. All catheters showed adherent thrombi on their external surface. The internal surface of three catheters showed evidence of thrombosis. Polyethylene differed from polyurethane in several respects. Although the external surface had an irregular and wavelike appearance, the internal surface was smooth and regular. Two polyethylene catheters showed thrombi on their external surface. The internal surface of one catheter showed single platelets in one area. These results confirm recent reports showing that internal and external surface irregularities play a major role in the initiation of thrombosis in and on intravascular catheters. They stress the need for high quality catheter materials with smooth and regular surfaces in the prevention of thromboembolic complications from coronary arteriography.
在进行常规冠状动脉造影后，通过扫描电子显微镜对6根Ducor聚氨酯冠状动脉导管和6根RPX聚乙烯冠状动脉导管的内外壁表面不规则情况及血栓形成进行了研究。聚氨酯导管的内外表面粗糙且极不规则。所有导管的外表面均有附着血栓。3根导管的内表面有血栓形成迹象。聚乙烯在几个方面与聚氨酯不同。尽管其外表面呈不规则波浪状，但内表面光滑规则。两根聚乙烯导管的外表面有血栓。一根导管的内表面在一个区域有单个血小板。这些结果证实了最近的报道，即内外表面不规则在血管内导管内及导管上血栓形成的起始过程中起主要作用。它们强调了在预防冠状动脉造影血栓栓塞并发症方面，需要使用具有光滑规则表面的高质量导管材料。
